Pregabalin

The history of pregabalin dates back to the late 1980s and early 1990s, when chemist Richard Bruce Silverman and his team at Northwestern University began synthesizing compounds that could have an impact on neurological disorders. The objective was to create a compound that would interact with neurons, and decrease the release of certain neurotransmitters. 

Silverman and his team patented the molecule of pregabalin in 1990. Pfizer then purchased the patent, and continued with the development and clinical testing of the compound. It was found to be effective in the treatment of certain diseases. As the active ingredient in Lyrica, pregabalin was first approved by the European Medicines Agency in 2004 to be sold to the public. It was subsequently approved by the U. S. Food and Drug Administration (FDA) in 2005.

Our online pharmacy carries a wide variety of licensed and approved products to meet all your healthcare needs, including sleeping pills, pain relievers, anxiety medication, and nootropics. Your orders are delivered to your doorstep, and we provide a parcel tracking service to ensure that it gets to you on time. 

What is Pregabalin Used For?    

People buy pregabalin for neuropathic pain, which is pain that originates from damaged nerves. This kind of pain may be due to diabetic neuropathy, where long-term diabetes impacts the nerves. It can also be caused by postherpetic neuralgia, which occurs after a shingles infection. It achieves this by suppressing the activity of nerves that are overactive, and by decreasing the signals that are sent to the brain.   

This makes it effective in the treatment of chronic pain, which is hard to control using normal pain relievers. Besides nerve pain, pregabalin is also used for the treatment of generalized anxiety disorder in adults. It assists in reducing the amount of worrying and anxiety by changing some of the chemicals in the brain that control mood. It is used for treating anxiety, which affects the patient’s ability to function normally.   

Pregabalin is also used in the management of epilepsy, more specifically as an add-on treatment for partial seizures. It does not cure epilepsy, but it helps in controlling seizures by regulating electrical signals in the brain. In this role, it is usually prescribed together with other anti-seizure drugs in order to enhance the management of the condition.  

Pregabalin Side Effects  

The side effects of pregabalin are usually mild, but in rare cases may be severe. The most common side effect is dizziness, which can interfere with daily activities and may lead to accidents while driving or operating machinery. In addition to this, many people suffer from dizziness or fatigue, which is a condition that makes the affected person feel extremely tired during the day.    

These side effects are temporary, but can interfere with a person’s focus or their capacity to do specific tasks. Another side effect is weight gain, and this may be attributed to fluid retention or increased appetite. Some people may also develop oedema which is the swelling of the hands, feet or ankles. This may be painful, and if it gets worse, one should consult a doctor.   

Also, dry mouth is a common problem, which causes discomfort and the desire to drink more water. Pregabalin may also have an impact on the mental and emotional state of a person. Others complain of feeling as if they are spinning, or have foggy vision.  

Although such effects are short-term, they can be worrisome and may impact the ability to carry out everyday activities. The severe but rare side effects include the alteration of mood or behaviour such as increased anxiety, depression or even suicidal thoughts. If this occurs, it is advisable to consult a doctor as soon as possible. It’s important to be knowledgeable about side effects before you buy pregabalin.   

How Does Pregabalin Work?  

Pregabalin is an anticonvulsant drug that affects the activity of neurotransmitters in the brain to help alleviate pain and seizures. It impacts the transmission of pain signals through nerves, and changes the brain’s functioning. Pregabalin is known to interact with a specific subunit of voltage-gated calcium channels in the CNS. It binds to these channels, and reduces the entry of calcium ions into nerve cells by preventing their access to the channel.   

This inhibition decreases the output of neurotransmitters, which are substances that relay pain messages, and cause an irregular firing of neurons in the brain. In neuropathic pain, for example, it helps reduce the excessive activity of nerve cells that transmit pain signals to the brain. This assists in the management of chronic pain, since the nerves are eased and pain signals are supressed.   

In epilepsy, pregabalin helps control abnormal electrical signals in the brain, and decrease the occurrence of seizures. It works by regulating the overactive nerves that cause seizures, and therefore prevents the seizures from happening. In the case of GAD, it has an impact on the neurotransmitters which cause anxiety symptoms. 

The medication assists in regulating the chemicals in the brain which are responsible for mood and emotions. This helps to relieve excessive worrying and anxiety.  

Pregabalin Dosage   

The dosage of pregabalin depends on the condition and the characteristics of the patient. In treating neuropathic pain, the recommended starting dose is 75 mg twice daily, or 50 mg three times daily. The dose can be increased or decreased depending on the patient’s reaction and the side effects experienced.   

The usual recommended doses are between 150 to 600 mg per day, which can be taken in the morning and evening, or in the morning, afternoon and night. The daily dose should not exceed 600 mg. When used for GAD, pregabalin typically begins at 150 mg per day, given in two or three divided doses. 

Depending on the patient’s response and the level of tolerability, the dose can be adjusted, and the effective dose is within the range of 300-600 mg per day. The maximum dose for GAD is 600 milligrams per day. In epilepsy, pregabalin is also started at 150 mg per day, which may again be given in two or three divided doses.   

The dose may be increased by increments according to the patient’s seizure control and tolerance, with the daily dose usually ranging between 300-600 mg. The initial dose for fibromyalgia is 75 mg twice daily, and may be increased to a maximum of 300 mg per day.   

Pregabalin Safety  

Pregabalin should not be combined with certain drugs because it may reduce the effectiveness, and increase the likelihood of adverse reactions. If used together with other drugs that cause central nervous system (CNS) depression, such as alcohol, benzodiazepines, or opioids, it may increase the sedative effect of these drugs. This may cause increased drowsiness, dizziness, and decreased mental and physical performance.   

Patients who buy pregabalin should be careful, and seek medical advice if they are using these substances together with it. It also interacts with other antiepileptic drugs. For example, it can affect the levels of carbamazepine or valproate in the body, which can reduce their efficacy and increase the risk of side effects. In order to control these interactions, healthcare providers might have to change the doses of the drugs involved.   

It is not advised for use in patients with certain health conditions. It should be used with caution in any patient with a history of kidney disease, since it is primarily metabolized by the kidneys. Dose adjustment may be required in patients with renal impairment.   

Also, UK patients with a history of substance abuse should be observed more carefully, since it may cause dependency in some cases. Pregabalin should also be taken with caution in pregnant or breastfeeding women, because its impact on the foetus or the infant is unknown.  

Pregabalin Reviews  

Reviews are very useful in online shopping, as they offer information about products and services. Pregabalin reviews are useful to patients, online platforms, and the new users who are looking for the right websites to buy pregabalin from. Reviews are an effective way of communication that allows customers to express their opinions regarding products and services. These reviews are particularly important to online platforms, as they contain a lot of information.   

Positive reviews reveal the products that perform well, while negative reviews reveal areas of weakness. This feedback loop assists websites to improve their products and services, enhancing the quality of the products and services being offered. The opinions and experiences of pregabalin users can be presented in the form of anecdotes.  

This empowerment is important, as it makes sure that the businesses are responsible for the quality of their products. It also creates an environment of transparency, credibility, and equity that is crucial in the development of customer business relations. 

Exploring Pregabalin Benefits

Pregabalin is an anticonvulsant drug that has several advantages, mainly in the treatment of conditions that involve neuropathic pain or neurological disorders. It has a positive effect on people who are afflicted with these debilitating health conditions. It is most useful in managing neuropathic pain, which is usually difficult to manage with the use of standard analgesics. 

It assists in the management of conditions such as diabetic neuropathy, post-herpetic neuralgia and fibromyalgia, enhancing the life of patients with chronic pain. Pregabalin is also used in the management of some types of seizures, which gives better control of epileptic attacks. This is especially important for epileptic patients, since it helps to minimize the number of seizures and their severity. 

It is also used in some cases for the treatment of generalized anxiety disorder. It has a sedative effect on the nervous system, and helps people with anxiety to cope with their emotions and gain control over them. It can also help those with insomnia to have better quality sleep. This is why people in the UK buy pregabalin.

Before You Buy Pregabalin   

Patients are now able to purchase pregabalin online, which is a very effective way of getting medication without any embarrassment. Our online pharmacy is focused on delivering a safe and enjoyable shopping experience to customers interested in purchasing prescription drugs. When you order medicine through our online store, you can be assured of absolute discretion.   

We respect the privacy of our clients, and our services involve secure and anonymous transactions and deliveries from the time of placing an order. We have the option of buying in bulk, where the customer is able to make larger orders at a cheaper price per unit. This is especially beneficial to those who need medication on a daily basis. Our prices are competitive, to ensure that you get the best average prices compared to other vendors.   

Our online pharmacy is always available, which gives buyers the opportunity to purchase pregabalin in the UK at any time they wish. It does not have fixed working hours, and does not require the client to go to a physical pharmacy. Discreet, affordable, and open 24/7, we strive to be the go-to source for pregabalin.   

Buy Pregabalin Online Prescription Free   

We are here to offer you an easy and safe way to order medication at our online pharmacy in the UK. Begin with our easily navigable website, where you can search for medications. Select the amount of pregabalin that will suit you. Proceed to the checkout, and you will be able to pay for the order. We offer our clients secure and convenient payment methods such as Visa and MasterCard, so your financial data is safe.   

If you want to pay with bitcoin, then we have a special offer for you. You can purchase pregabalin with bitcoin, and get free shipping as well as additional tablets. If you have any questions or need help during your buying process, our customer support team is here to assist you. It is possible to contact them through email, live chat, or phone to get professional and fast help.   

Safe payment methods, a bitcoin promotion for extra benefits, and easy access to our customer support team are some of the ways we strive to make your experience with us as smooth as possible. 

Buy pregabalin in the UK at pharmacy4uk.net and put an end to persistent pain.  

Last Reviewed: 16th September 2024
Next Review Due: October 2025